Small batch sizes and the need for flexible filling systems and processes are driving the pharmaceutical industry: with the MultiUse concept, Optima Pharma shows how pharmaceutical companies can respond to small batch sizes and different container types. The company will also be presenting its Comprehensive Scientific Process Engineering (CSPE).
Highly specialised products in small quantities and a wide variety of dosage forms - this trend towards flexibility poses major challenges for pharmaceutical companies. It requires a rethink, as niche products require completely different production facilities than blockbusters. At the same time, it is essential not to neglect the high demands on product quality and patient safety. Optima Pharma is responding to this trend with multi-use systems:
They fill different primary packaging materials (vials, syringes, cartridges) and require less space. Users also save time thanks to an adjustable transport system that does not require format parts. A variety of technologies such as on-demand re-dosing, short hose lines, 1001TP3 tige-in-process control for vials, syringes and cartridges, on-demand weighing dosing or cap re-setting help to minimise product losses.
CSPE in response to current developments in sterile filling
The requirements of users in the pharmaceutical and biotech industries are changing. The decision in favour of a particular machine configuration is being made later and later in the course of a project. In order to respond to this change, Optima Pharma has developed the CSPE process developed. Comprehensive Scientific Process Engineering is revolutionising the digitalised design, planning and implementation of pharmaceutical filling systems and will be presented at the trade fair. The combination of scientific methods and technological processes minimises the time between the order and the start of production.
These include simulations that can be used to recognise and avoid problem areas of laminar flow (see image above) as early as the design phase. VHP decontamination can also be simulated. This shows at an early stage whether all surfaces inside the machine can be reached. The simulation significantly reduces the development time.
Digital solutions support operators
The specialists at Optima Pharma will be demonstrating the helpful digital technologies they have developed on the SV125 trade fair machine. To facilitate safe and fast format changeovers, the company has developed a process for labelling format parts with 2D matrix codes. Scanning the codes tells the operator how to position the format part correctly. This prevents damage caused by incorrectly fitted format parts. Fast and convenient troubleshooting is the result of a new HMI display, which will also be on show at the trade fair machine. Machine performance data will be visualised on it, enabling machine operation to be optimised. Instead of an error line, the HMI shows a clear three-dimensional machine model.
OPTIMA Pharma at ACHEMA 2018: Hall 3, Stand A73
