Steriline robot fills individual syringes

It was the wish of a single manufacturer. The result is a robotic nest filling machine that also enables other pharmaceutical companies to fill individual syringes cost-effectively. Steriline presented this solution at the recently concluded PHARMINTECH trade fair in Milan.

It was the wish of a single manufacturer. The result is a robotic nest filling machine that also enables other pharmaceutical companies to fill individual syringes cost-effectively. Steriline presented this solution at the recently concluded PHARMINTECH trade fair in Milan.

The idea came from an Italian manufacturer of veterinary medicines that wanted to expand its product portfolio by adding pre-filled single-dose glass syringes (VEG) to the multiple-dose vials it already produced. Steriline then developed a complete robotic nest filling machine as a stand-alone solution. It bears the name RNFM2 and is equipped with two filling heads and peristaltic pumps.

Interior view of the RNFM2 (Photo: Steriline)

Simultaneous filling and tamping

The machine is equipped with two manual loading and unloading stations, into which an operator inserts the tubs that have previously been freed from their packaging bags under a laminar air flow. A robot arm picks up the nest with the empty VEG in the tub and positions it under the two filling heads, which are connected to the peristaltic pumps. The glass containers can now be filled with any filling quantity from 0.1 ml. In addition to the double filling heads, the machine is also equipped with two stoppering heads. Filling and stoppering are performed simultaneously. Once the process is complete, the robot arm positions the tub back in the nest at the dispensing station so that the operator can remove it and feed it into the secondary packaging process.

The machine on display has a footprint of 1.250 m x 1.250 m under the Open Restricted Access Barrier System (ORABS), but can also be equipped with isolators if this is required for the process. It has a production capacity of up to 2,900 units/hour and is designed to process 0.5 ml pre-filled single-dose glass syringes. The machine allows for easy format changeovers, resulting in a very flexible solution that can be easily adapted to new company requirements.

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